Adam Reeve

Research

Representative volume element of vascularised tissue.
Slice through the knee showing the bone density distribution predicted by the model.

For my PhD thesis I investigated how blood pressure affects the mechanical behaviour of tissue, developed methods for coupling blood pressure to mechanics in computational models of vascularised tissue, and applied these methods to a model of the left ventricle of the heart.

In my undergraduate honours project, I developed a computational model of bone growth in the knee for modelling the progression of osteoarthritis.

Publications

Reeve, A. M. (2014). The mechanics of vascularised tissue. Doctoral thesis. The University of Auckland. URL

Reeve, A. M., M. P. Nash, A. J. Taberner, and P. M. F. Nielsen (2014). Constitutive relations for pressure-driven stiffening in poroelastic tissues. Journal of Biomechanical Engineering, 136(8), 081011. DOI

Reeve, A. M., A. J. Taberner, M. P. Nash, and P. M. F. Nielsen (2013). Perfusion pressure driven stiffening in vascularised tissue. In Proceedings of the 11th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, 111–112.

Bradley, C., A. Bowery, R. Britten, V. Budelmann, O. Camara, R. Christie, A. Cookson, A. F. Frangi, T. P. Babarenda Gamage, T. Heidlauf, S. Krittian, D. Ladd, C. Little, K. Mithraratne, M. Nash, D. Nickerson, P. Nielsen, Ø. Nordbø, S. Omholt, A. Pashaei, D. Paterson, V. Rajagopal, A. Reeve, O. Röhrle, S. Safaei, R. Sebastián, M. Steghöfer, T. Wu, T. Yu, H. Zhang, and P. Hunter (2011). OpenCMISS: A multi-physics & multi-scale computational infrastructure for the VPH/Physiome project. Progress in Biophysics and Molecular Biology, 107(1), 32–47. DOI

Reeve, A. M., A. Garny, A. K. Miller, and R. D. Britten (2010). Biological modelling using CellML and MATLAB. The Open Pacing, Electrophysiology & Therapy Journal, 3(1), 60–65. URL

Miller, A. K., J. Marsh, A. Reeve, A. Garny, R. Britten, M. Halstead, J. Cooper, D. P. Nickerson, and P. M. F. Nielsen (2010). An overview of the CellML API and its implementation. BMC Bioinformatics, 11, 178. DOI

Reeve, A. M. (2009). Modelling the development of osteoarthritis in the human knee joint. Undergraduate honours thesis. The University of Auckland. PDF